Obesity Inflammasome as a Risk for Developing Gestational Diabetes
27 Apr 2021 19:00 - 20:00 - Webinar
This webinar is part of the Diabetes and Obesity in Pregnancy: From Patients to Molecular Mechanisms series.
This webinar is the first of three sessions boarding the consequences on cellular and molecular levels of maternal obesity and gestational diabetes in the mother/foetus physiology in unhealthy pregnancies. Professor Dmitri Mikhailidis (University College London, UK), Editor-in-Chief of Current Vascular Pharmacology, will briefly introduce the series.
Dr Padma Murthy (Monash University, Melbourne, Australia) will cover pharmacological inhibition of upstream and downstream targets of the inflammasome signalling cascade and the inflammasome platform as a potential therapeutic strategy attenuating the pathophysiology underpinning the inflammatory component in maternal obesity.
Professor David Hill (Lawson Health Research Institute, London, Canada) will discuss how maternal obesity during pregnancy can create a pro-inflammatory environment that can disrupt the response of the β-cells to the endocrine signals of pregnancy and limit the adaptive changes in β-cell mass and function, resulting in an increased risk of gestational diabetes.
Please note that there is a £20.00 registration fee for non-members*. This includes 7-day access to the recording.
*If you are a member of the following societies, you are eligible for free registration. Please email events@physoc.org with proof of membership for the appropriate discount code.
- Latin American Association of Physiological Sciences (ALACF)
- Chilean Society of Obstetrics and Gynaecology (SOCHOG)
- Chilean Society of Physiological Sciences (SCHCF)